Interactor 1: IL17 (Q62386)
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Gene: Il17a

Interactor 2: I17RC (Q8K4C2)
Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14)
Gene: Il17rc

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21993849
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL17~IL17_R_N
Common GO terms GO:0006954 - inflammatory response
GO:0032755 - positive regulation of interleukin-6 production
GO:0038173 - interleukin-17A-mediated signaling pathway
GO:0050832 - defense response to fungus
GO:1900017 - positive regulation of cytokine production involved in inflammatory response
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 158
Mm

1 698
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024