Interactor 1: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Interactor 2: TIFA (Q793I8)
TRAF-interacting protein with FHA domain-containing protein A (TRAF2-binding protein)
Gene: TIFA

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.690

The method score is based on:

Property Details
Experiments 12566447
Identification Methods anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FHA~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045087 - innate immune response
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 710
Mm

1 184
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024