HitPredict

Interactor 1: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Interactor 2: IRAK3 (Q8K4B2)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 15833358, 19166926
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 8 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 710
Mm

1 609
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024