Interactor 1: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Interactor 2: TLR9 (Q9EQU3)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21911421
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005149 - interleukin-1 receptor binding
GO:0005886 - plasma membrane
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045087 - innate immune response
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 710
Mm

1 1032
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024