HitPredict

Interactor 1: SMAD2 (Q62432)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2) (SMAD family member 2) (SMAD 2) (Smad2)
Gene: SMAD2

Interactor 2: Q8BTS0 (Q8BTS0)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5)
Gene: Ddx5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15464984
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0070412 - R-SMAD binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 467 Mm			1 615
+	Mm
		1207259 SMAD3_MOUSE (1-467): 0: 621: 83.94		Q8BTS0_MOUSE (1-615): 0: 614: 100.00
+	Hs
		571401 SMAD3_HUMAN (1-467): 0: 621: 83.94		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Mm
		936615 SMAD1_MOUSE (1-467): 0: 575: 55.42		Q8BTS0_MOUSE (1-615): 0: 614: 100.00
+	Hs
		571568 SMAD5_HUMAN (1-467): 0: 579: 55.45		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Hs
		571470 SMAD1_HUMAN (1-467): 0: 573: 55.53		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Hs
		181701 SMAD2_HUMAN (1-467): 0: 679: 99.57		DDX3Y_HUMAN (3-485): 3.4e-148: 445: 37.40
+	Hs
		133977 SMAD3_HUMAN (1-467): 0: 621: 83.94		DDX3X_HUMAN (3-478): 1.97e-148: 445: 38.66
+	Hs
		181693 SMAD3_HUMAN (1-467): 0: 621: 83.94		DDX3Y_HUMAN (3-485): 3.4e-148: 445: 37.40
+	Mm
		956548 SMAD4_MOUSE (11-456): 5.89e-144: 425: 31.63		Q8BTS0_MOUSE (1-615): 0: 614: 100.00
+	Mm
		192488 SMAD7_MOUSE (13-443): 6.38e-113: 341: 25.06		Q8BTS0_MOUSE (1-615): 0: 614: 100.00