Interactor 1: UN13A (Q62768)
Protein unc-13 homolog A (Munc13-1)
Gene: Unc13a

Interactor 2: RIMS2 (Q9JIS1)
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2)
Gene: RIMS2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.730

The method score is based on:

Property Details
Experiments 16732694
Identification Methods isothermal titration calorimetry, molecular sieving, nuclear magnetic resonance, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C2, C2~C2
Common GO terms GO:0007269 - neurotransmitter secretion
GO:0016081 - synaptic vesicle docking
GO:0016082 - synaptic vesicle priming
GO:0019904 - protein domain specific binding
GO:0030154 - cell differentiation
and 6 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1735
Rn

1 1555
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024