HitPredict

Interactor 1: NLGN2 (Q62888)
Neuroligin-2
Gene: NLGN2

Interactor 2: DLG3 (Q62936)
Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)
Gene: DLG3

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15458844
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0043198 - dendritic shaft GO:0045202 - synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 836 Rn			1 849
+	Rn
		1144023 NLGN1_RAT (1-836): 0: 923: 61.00		DLG3_RAT (1-849): 0: 707: 100.00
+	Hs
		1271033 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG3_HUMAN (1-849): 0: 680: 95.29
+	Hs
		1231765 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG3_HUMAN (1-849): 0: 680: 95.29
+	Hs
		1245078 NLGN2_HUMAN (1-836): 0: 904: 98.09		DLG3_HUMAN (1-849): 0: 680: 95.29
+	Mm
		1143408 NLGN3_MOUSE (1-836): 0: 946: 62.76		DLG4_MOUSE (100-849): 0: 572: 62.95
+	Hs
		942360 NLGNX_HUMAN (1-836): 0: 944: 60.85		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Mm
		57108 A2AGI2_MOUSE (1-836): 0: 943: 60.98		DLG4_MOUSE (100-849): 0: 572: 62.95
+	Hs
		942388 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Mm
		1143338 NLGN2_MOUSE (1-836): 0: 936: 99.88		DLG4_MOUSE (100-849): 0: 572: 62.95
+	Rn
		677789 NLGN2_RAT (1-836): 0: 933: 100.00		DLG4_RAT (100-849): 0: 572: 62.82
+	Hs
		942361 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Rn
		677788 NLGN1_RAT (1-836): 0: 923: 61.00		DLG4_RAT (100-849): 0: 572: 62.82
+	Hs
		942363 NLGN2_HUMAN (1-836): 0: 904: 98.09		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Hs
		1077290 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG2_HUMAN (315-690): 3.67e-21: 101: 17.88
+	Rn
		1144055 NLGN2_RAT (1-836): 0: 933: 100.00		DLG2_RAT (315-691): 6.7e-22: 103: 17.83
+	Hs
		1077282 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG2_HUMAN (315-690): 3.67e-21: 101: 17.88
+	Rn
		1144025 NLGN1_RAT (1-836): 0: 923: 61.00		DLG2_RAT (315-691): 6.7e-22: 103: 17.83
+	Dm
		677696 Q7KT70_DROME (12-634): 4.84e-156: 482: 28.81		DLG1_DROME (4-849): 2.29e-172: 525: 46.33
+	Hs
		1077283 NLGN2_HUMAN (1-836): 0: 904: 98.09		DLG2_HUMAN (315-690): 3.67e-21: 101: 17.88