HitPredict

Interactor 1: NLGN2 (Q62888)
Neuroligin-2
Gene: NLGN2

Interactor 2: DLG2 (Q63622)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15458844
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0019233 - sensory perception of pain GO:0045211 - postsynaptic membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 836 Rn			1 852
+	Rn
		1144025 NLGN1_RAT (1-836): 0: 923: 61.00		DLG2_RAT (1-852): 0: 751: 100.00
+	Hs
		1077290 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG2_HUMAN (1-852): 0: 725: 94.94
+	Hs
		1077282 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG2_HUMAN (1-852): 0: 725: 94.94
+	Hs
		1077283 NLGN2_HUMAN (1-836): 0: 904: 98.09		DLG2_HUMAN (1-852): 0: 725: 94.94
+	Mm
		1143408 NLGN3_MOUSE (1-836): 0: 946: 62.76		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		942360 NLGNX_HUMAN (1-836): 0: 944: 60.85		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Mm
		57108 A2AGI2_MOUSE (1-836): 0: 943: 60.98		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		942388 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Mm
		1143338 NLGN2_MOUSE (1-836): 0: 936: 99.88		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		1271033 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG3_HUMAN (10-366): 1.42e-29: 128: 16.80
+	Rn
		677789 NLGN2_RAT (1-836): 0: 933: 100.00		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Hs
		942361 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Rn
		1144051 NLGN2_RAT (1-836): 0: 933: 100.00		DLG3_RAT (10-391): 7.38e-29: 126: 17.87
+	Hs
		1231765 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG3_HUMAN (10-366): 1.42e-29: 128: 16.80
+	Rn
		677788 NLGN1_RAT (1-836): 0: 923: 61.00		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Rn
		1144023 NLGN1_RAT (1-836): 0: 923: 61.00		DLG3_RAT (10-391): 7.38e-29: 126: 17.87
+	Hs
		942363 NLGN2_HUMAN (1-836): 0: 904: 98.09		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Hs
		1245078 NLGN2_HUMAN (1-836): 0: 904: 98.09		DLG3_HUMAN (10-366): 1.42e-29: 128: 16.80
+	Dm
		677696 Q7KT70_DROME (12-634): 4.84e-156: 482: 28.81		DLG1_DROME (39-852): 2.12e-159: 491: 49.83