HitPredict

Interactor 1: NLGN2 (Q62888)
Neuroligin-2
Gene: NLGN2

Interactor 2: MAGI3 (Q9JK71)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)
Gene: MAGI3

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15458844
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 836 Rn			1 1470
+	Rn
		291506 NLGN2_RAT (1-836): 0: 933: 100.00		MAGI2_RAT (655-1468): 5.6e-43: 174: 15.02
+	Rn
		291504 NLGN1_RAT (1-836): 0: 923: 61.00		MAGI2_RAT (655-1468): 5.6e-43: 174: 15.02
+	Mm
		1143408 NLGN3_MOUSE (1-836): 0: 946: 62.76		DLG4_MOUSE (1-239): 2.13e-19: 96.7: 10.20
+	Hs
		942360 NLGNX_HUMAN (1-836): 0: 944: 60.85		DLG4_HUMAN (1-239): 2.95e-19: 96.3: 10.20
+	Mm
		57108 A2AGI2_MOUSE (1-836): 0: 943: 60.98		DLG4_MOUSE (1-239): 2.13e-19: 96.7: 10.20
+	Hs
		1077290 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG2_HUMAN (2-209): 2.3e-19: 96.7: 14.09
+	Hs
		942388 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG4_HUMAN (1-239): 2.95e-19: 96.3: 10.20
+	Mm
		1143338 NLGN2_MOUSE (1-836): 0: 936: 99.88		DLG4_MOUSE (1-239): 2.13e-19: 96.7: 10.20
+	Rn
		677789 NLGN2_RAT (1-836): 0: 933: 100.00		DLG4_RAT (1-239): 1.19e-19: 97.5: 10.61
+	Hs
		1077282 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG2_HUMAN (2-209): 2.3e-19: 96.7: 14.09
+	Hs
		942361 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG4_HUMAN (1-239): 2.95e-19: 96.3: 10.20
+	Rn
		677788 NLGN1_RAT (1-836): 0: 923: 61.00		DLG4_RAT (1-239): 1.19e-19: 97.5: 10.61
+	Hs
		1271033 NLGN3_HUMAN (1-836): 0: 938: 60.87		DLG3_HUMAN (944-1382): 1.06e-12: 75.1: 12.89
+	Rn
		1117609 NLGN2_RAT (1-836): 0: 933: 100.00		MAGI1_RAT (976-1377): 1.03e-13: 78.6: 14.59
+	Rn
		1144055 NLGN2_RAT (1-836): 0: 933: 100.00		DLG2_RAT (936-1348): 1.61e-12: 74.7: 11.64
+	Hs
		1231765 NLGN1_HUMAN (2-836): 0: 931: 59.46		DLG3_HUMAN (944-1382): 1.06e-12: 75.1: 12.89
+	Rn
		1144051 NLGN2_RAT (1-836): 0: 933: 100.00		DLG3_RAT (934-1382): 1.56e-11: 71.3: 12.83
+	Rn
		1117608 NLGN1_RAT (1-836): 0: 923: 61.00		MAGI1_RAT (976-1377): 1.03e-13: 78.6: 14.59
+	Rn
		1144025 NLGN1_RAT (1-836): 0: 923: 61.00		DLG2_RAT (936-1348): 1.61e-12: 74.7: 11.64
+	Rn
		1144023 NLGN1_RAT (1-836): 0: 923: 61.00		DLG3_RAT (934-1382): 1.56e-11: 71.3: 12.83