Interactor 1: M3K1 (Q62925)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)
Gene: Map3k1

Interactor 2: M3K1 (Q62925)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)
Gene: Map3k1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.735

The method score is based on:

Property Details
Experiments 11784851
Identification Methods protein kinase assay, anti tag coimmunoprecipitation
Interaction Type phosphorylation reaction, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0000209 - protein polyubiquitination
GO:0002011 - morphogenesis of an epithelial sheet
GO:0003382 - epithelial cell morphogenesis
GO:0004672 - protein kinase activity
and 37 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1493
Rn

1 1493
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024