HitPredict

Interactor 1: GRID2 (Q63226)
Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)
Gene: GRID2

Interactor 2: DLG2 (Q63622)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	10234023
Identification Methods	cross-linking study, anti bait coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030165 - PDZ domain binding GO:0045211 - postsynaptic membrane GO:0098839 - postsynaptic density membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1007 Rn			1 852
+	Rn
		1143996 GRID1_RAT (13-1007): 0: 773: 55.75		DLG2_RAT (1-852): 0: 751: 100.00
+	Mm
		620904 GRIA1_MOUSE (3-889): 0: 718: 24.45		DLG2_MOUSE (1-852): 0: 752: 99.77
+	Mm
		1142965 GRID2_MOUSE (1-1007): 0: 920: 99.50		DLG1_MOUSE (8-852): 6.05e-172: 522: 53.34
+	Rn
		1144011 GRID2_RAT (1-1007): 0: 921: 100.00		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Hs
		1021483 GRIK2_HUMAN (8-924): 0: 733: 26.82		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Hs
		786696 GRIA1_HUMAN (6-915): 0: 725: 24.28		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Rn
		585151 GRIA1_RAT (3-889): 0: 720: 24.56		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Mm
		1142961 GRID2_MOUSE (1-1007): 0: 920: 99.50		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Rn
		677792 GRID2_RAT (1-1007): 0: 921: 100.00		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Mm
		1142983 GRID1_MOUSE (13-1007): 0: 774: 55.66		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		761199 GRIK1_HUMAN (4-860): 0: 737: 27.53		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Hs
		942335 GRIK2_HUMAN (8-924): 0: 733: 26.82		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Mm
		761217 GRIK2_MOUSE (8-924): 0: 732: 26.82		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Rn
		677766 GRIK2_RAT (8-924): 0: 732: 26.82		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Hs
		1022366 GRIK2_HUMAN (8-924): 0: 733: 26.82		DLG3_HUMAN (10-366): 1.42e-29: 128: 16.80
+	Rn
		585138 GRIA1_RAT (3-889): 0: 720: 24.56		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Mm
		620892 GRIA1_MOUSE (3-889): 0: 718: 24.45		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Mm
		620881 GRIA1_MOUSE (3-889): 0: 718: 24.45		DLG3_MOUSE (10-391): 1.11e-28: 125: 17.87
+	Mm
		1143565 GRIA4_MOUSE (1-875): 0: 709: 25.19		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		786757 GRIA3_HUMAN (3-871): 0: 706: 25.34		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37