HitPredict

Interactor 1: PRS7 (Q63347)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: Psmc2

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Rn			1 810
+	Rn
		906974 PRS4_RAT (1-428): 7.22e-137: 401: 40.00		UBC_RAT (1-810): 0: 1000: 100.00
+	Rn
		102498 G3V6W6_RAT (39-429): 1.24e-120: 358: 42.46		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		475422 PRS7_HUMAN (1-433): 4.12e-147: 427: 99.77		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475570 PRS8_HUMAN (40-430): 1.47e-121: 361: 45.27		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475580 PRS10_HUMAN (39-429): 7.48e-121: 358: 42.46		UBC_HUMAN (1-533): 0: 662: 99.81
+	Sc
		477414 PRS8_YEAST (16-417): 8.12e-154: 443: 44.28		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	Sc
		477201 PRS7_YEAST (1-433): 4.69e-130: 384: 69.17		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	At
		1092378 PRS7A_ARATH (10-433): 8.88e-142: 413: 80.19		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091962 PRS8A_ARATH (4-430): 6.09e-125: 370: 44.86		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091926 PRS8B_ARATH (33-430): 5.13e-124: 368: 46.37		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092257 PS10B_ARATH (26-429): 1.19e-122: 363: 41.09		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092307 PS10A_ARATH (35-429): 2.18e-122: 362: 41.56		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		730236 PRS7_HUMAN (1-433): 4.12e-147: 427: 99.77		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476889 Q8BVQ9_MOUSE (1-433): 7.1e-147: 428: 99.54		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		476744 PRS4_MOUSE (1-428): 7.22e-137: 401: 40.00		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		906982 PRS8_HUMAN (40-430): 1.47e-121: 361: 45.27		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		913239 PRS10_HUMAN (39-429): 7.48e-121: 358: 42.46		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476745 PRS8_MOUSE (40-430): 1.47e-121: 361: 45.27		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		476747 PRS10_MOUSE (39-429): 7.48e-121: 358: 42.46		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		397886 PRS10_HUMAN (39-429): 7.48e-121: 358: 42.46		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69