HitPredict

Interactor 1: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Interactor 2: OPTN (Q8R5M4)
Optineurin (FIP-2-like protein)
Gene: OPTN

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CC2-LZ~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 810 Rn			1 585
+	Hs
		476176 UBC_HUMAN (1-533): 0: 662: 99.81		OPTN_HUMAN (1-585): 2.27e-43: 165: 77.37
+	Hs
		475816 UBC_HUMAN (1-533): 0: 662: 99.81		ITSN1_HUMAN (30-420): 3.82e-37: 150: 18.41
+	Hs
		476660 UBC_HUMAN (1-533): 0: 662: 99.81		NEMO_HUMAN (207-584): 1.66e-36: 142: 25.79
+	Hs
		475291 UBC_HUMAN (1-533): 0: 662: 99.81		MYH1_HUMAN (8-511): 2.1e-17: 88.7: 10.52
+	Hs
		475417 UBC_HUMAN (1-533): 0: 662: 99.81		MYH9_HUMAN (228-574): 3.72e-12: 71.8: 11.11
+	Hs
		475882 UBC_HUMAN (1-533): 0: 662: 99.81		FKB15_HUMAN (47-441): 6.55e-11: 67.4: 13.55
+	Hs
		475789 UBC_HUMAN (1-533): 0: 662: 99.81		PLEC_HUMAN (38-540): 6.14e-09: 61.2: 11.44
+	Hs
		924113 RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00		OPTN_HUMAN (1-585): 2.27e-43: 165: 77.37
+	Mm
		291775 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		NEMO_MOUSE (215-584): 1.58e-37: 145: 26.74
+	Hs
		475130 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		OPTN_HUMAN (1-585): 2.27e-43: 165: 77.37
+	Hs
		475262 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		NEMO_HUMAN (207-584): 1.66e-36: 142: 25.79
+	Hs
		148651 RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00		CTRO_HUMAN (116-561): 5.66e-11: 67.8: 14.00
+	Mm
		477062 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		ITSN1_MOUSE (70-459): 1.49e-15: 82.8: 11.54
+	Mm
		476828 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		MYH10_MOUSE (2-396): 7.67e-14: 77.2: 11.69
+	Mm
		476930 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		MYH9_MOUSE (228-574): 8.13e-12: 70.6: 11.11
+	Mm
		476960 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		MYO5A_MOUSE (38-471): 1.97e-10: 66.2: 15.91
+	Hs
		397814 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		MYH10_HUMAN (2-429): 8.72e-14: 76.8: 11.72
+	Hs
		398052 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		MY18A_HUMAN (38-488): 2.68e-12: 72: 11.50
+	Hs
		397813 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		MYH9_HUMAN (228-574): 3.72e-12: 71.8: 11.11
+	Hs
		397977 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		PLEC_HUMAN (38-540): 6.14e-09: 61.2: 11.44