HitPredict

Interactor 1: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Interactor 2: FAF1 (Q924K2)
FAS-associated factor 1
Gene: FAF1

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA_4~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 810 Rn			1 649
+	Hs
		476571 UBC_HUMAN (1-533): 0: 662: 99.81		FAF1_HUMAN (1-649): 0: 840: 95.39
+	Mm
		476721 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		FAF1_MOUSE (1-649): 0: 868: 98.61
+	Hs
		398140 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		FAF1_HUMAN (1-649): 0: 840: 95.39
+	Hs
		475246 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		FAF1_HUMAN (1-649): 0: 840: 95.39
+	Hs
		299310 UBC_HUMAN (1-533): 0: 662: 99.81		UBXN7_HUMAN (344-648): 1.02e-70: 239: 17.28
+	Hs
		476174 UBC_HUMAN (1-533): 0: 662: 99.81		FAF2_HUMAN (319-648): 1.05e-68: 232: 22.57
+	Hs
		475650 UBC_HUMAN (1-533): 0: 662: 99.81		UBXN1_HUMAN (413-648): 4.25e-34: 133: 16.00
+	Hs
		476327 UBC_HUMAN (1-533): 0: 662: 99.81		UBXN6_HUMAN (483-643): 8.75e-22: 100: 22.22
+	Sc
		477464 UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73		UBX5_YEAST (341-644): 1.35e-44: 168: 12.90
+	Sc
		477438 UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73		UBX2_YEAST (308-648): 1.42e-43: 166: 13.93
+	Mm
		476842 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		UBXN7_MOUSE (344-648): 2.93e-72: 242: 17.28
+	Mm
		476779 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		FAF2_MOUSE (319-648): 2.21e-68: 231: 22.57
+	Hs
		299309 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		UBXN7_HUMAN (344-648): 1.02e-70: 239: 17.28
+	Hs
		475128 UBB_HUMAN (1-77): 1.17e-26: 110: 98.70		FAF2_HUMAN (319-648): 1.05e-68: 232: 22.57
+	Mm
		476957 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		UBXN1_MOUSE (413-648): 7.32e-37: 141: 17.20
+	Hs
		397924 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		UBXN1_HUMAN (413-648): 4.25e-34: 133: 16.00
+	Mm
		476974 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		UBXN6_MOUSE (483-643): 1.97e-16: 84.1: 20.99
+	Hs
		398087 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		UBXN6_HUMAN (483-643): 8.75e-22: 100: 22.22