HitPredict

Interactor 1: DLG2 (Q63622)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Interactor 2: KCNJ2 (Q64273)
Inward rectifier potassium channel 2 (Inward rectifier K(+) channel Kir2.1) (IRK-1) (RBL-IRK1) (Potassium channel, inwardly rectifying subfamily J member 2)
Gene: KCNJ2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15304517
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030425 - dendrite GO:0043025 - neuronal cell body GO:0045211 - postsynaptic membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 852 Rn			1 427
+	Rn
		852400 DLG2_RAT (1-852): 0: 751: 100.00		KCJ12_RAT (2-427): 0: 678: 70.33
+	Hs
		1054723 DLG2_HUMAN (1-852): 0: 725: 94.94		KCJ12_HUMAN (2-427): 0: 690: 69.98
+	Hs
		816150 DLG2_HUMAN (1-852): 0: 725: 94.94		KCNJ4_HUMAN (30-427): 0: 606: 59.37
+	Hs
		929764 DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34		KCNJ2_HUMAN (1-427): 0: 729: 98.83
+	Rn
		1144015 DLG1_RAT (9-852): 4.45e-164: 502: 51.95		KCNJ2_RAT (1-427): 0: 728: 100.00
+	Hs
		1021490 DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34		KCJ12_HUMAN (2-427): 0: 690: 69.98
+	Hs
		80982 DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34		KCJ18_HUMAN (2-427): 0: 683: 69.28
+	Rn
		852397 DLG1_RAT (9-852): 4.45e-164: 502: 51.95		KCJ12_RAT (2-427): 0: 678: 70.33
+	Hs
		816147 DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34		KCNJ4_HUMAN (30-427): 0: 606: 59.37
+	Hs
		816159 DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34		KCNJ6_HUMAN (35-380): 0: 514: 53.16
+	Dm
		677699 DLG1_DROME (39-852): 2.12e-159: 491: 49.83		Q8IGY2_DROME (10-363): 2.49e-179: 509: 46.15
+	Hs
		929762 DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37		KCNJ2_HUMAN (1-427): 0: 729: 98.83
+	Hs
		942342 DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37		KCJ12_HUMAN (2-427): 0: 690: 69.98
+	Rn
		677769 DLG4_RAT (4-419): 7.48e-31: 131: 17.37		KCJ12_RAT (2-427): 0: 678: 70.33
+	Mm
		852403 DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37		KCNJ4_MOUSE (31-427): 0: 615: 59.18
+	Hs
		816146 DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37		KCNJ4_HUMAN (30-427): 0: 606: 59.37
+	Mm
		1143540 DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37		Q9QYK8_MOUSE (34-421): 0: 600: 58.80
+	Mm
		291382 DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37		KCNJ1_MOUSE (35-365): 3.39e-170: 483: 45.54
+	Mm
		1143568 DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37		KCJ16_MOUSE (32-370): 2.12e-167: 477: 49.26
+	Mm
		1143532 DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37		KCJ10_MOUSE (44-353): 1.8e-154: 443: 42.68