HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 716
+	Hs
		150716 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		DVL1_HUMAN (1-716): 8.84e-151: 456: 63.66
+	Hs
		151034 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		DVL2_HUMAN (3-716): 2.33e-133: 412: 65.13
+	Hs
		1067454 EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43		DVL3_HUMAN (1-716): 1.38e-173: 515: 100.00
+	Hs
		1113820 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		DVL3_HUMAN (1-716): 1.38e-173: 515: 100.00
+	Hs
		150999 EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43		DVL2_HUMAN (3-716): 2.33e-133: 412: 65.13
+	Hs
		150837 MYH7_HUMAN (588-1139): 1.75e-29: 129: 11.94		DVL2_HUMAN (3-716): 2.33e-133: 412: 65.13
+	Hs
		150759 DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99		DVL1_HUMAN (1-716): 8.84e-151: 456: 63.66
+	Hs
		1145894 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MAGI1_HUMAN (124-664): 2.49e-17: 89.2: 10.86
+	Hs
		1113813 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		PARD3_HUMAN (200-415): 1.34e-19: 96.2: 20.00
+	Hs
		724845 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		DIXC1_HUMAN (4-85): 2.43e-30: 129: 38.55
+	Hs
		1256910 DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99		PARD3_HUMAN (200-415): 1.34e-19: 96.2: 20.00
+	Hs
		724926 MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93		LNX1_HUMAN (127-369): 3.42e-14: 78.4: 17.07
+	Hs
		280085 DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99		MPDZ_HUMAN (228-333): 3.38e-11: 69.1: 29.46