HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 35709258
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0007099 - centriole replication
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 703
+	Hs
		1145962 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		DAPLE_HUMAN (37-586): 4.1e-41: 164: 17.08
+	Hs
		1012560 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		CGNL1_HUMAN (13-703): 9.98e-30: 128: 12.01
+	Hs
		725179 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		1113830 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		1113789 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		1145917 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		725097 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		725095 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		1067423 EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43		EEA1_HUMAN (231-701): 8.23e-14: 77.5: 11.62
+	Hs
		724687 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1113782 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		148466 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		148461 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		528435 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH4_HUMAN (2-477): 5.27e-17: 87.9: 10.65
+	Hs
		1113839 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		528432 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH13_HUMAN (314-702): 5.42e-12: 71.7: 14.00
+	Hs
		502901 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Hs
		528356 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH6_HUMAN (300-700): 3.66e-13: 75.5: 11.47