Interactor 1: E4F1 (Q66K89)
Transcription factor E4F1 (EC 2.3.2.27) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (RING-type E3 ubiquitin transferase E4F1) (Transcription factor E4F) (p120E4F) (p50E4F)
Gene: E4F1

Interactor 2: ZN574 (Q6ZN55)
Zinc finger protein 574
Gene: ZNF574

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C2H2~zf-C2H2, zf-C2H2~zf-met
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0046872 - metal ion binding
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 784
Hs

1 896
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024