HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: TRAF7 (Q6Q0C0)
E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.-) (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7)
Gene: TRAF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 670
+	Hs
		1074793 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		TAF5_HUMAN (98-669): 5.6e-83: 280: 14.17
+	Sc
		630844 NLE1_YEAST (42-474): 1.95e-50: 184: 12.40		NLE1_YEAST (380-669): 2.43e-72: 244: 23.53
+	Dm
		1358859 WDS_DROME (279-565): 1.49e-87: 278: 18.27		FBXW7_DROME (10-475): 2.16e-34: 142: 13.09
+	Dm
		1358845 WDS_DROME (279-565): 1.49e-87: 278: 18.27		WDS_DROME (124-427): 7.67e-20: 93.7: 11.25
+	Hs
		1346954 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		NLE1_HUMAN (119-503): 2.65e-45: 170: 13.81
+	Hs
		921751 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		NLE1_HUMAN (119-503): 2.65e-45: 170: 13.81
+	Hs
		903428 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21
+	Hs
		792935 LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98		LIS1_HUMAN (140-426): 1.68e-23: 105: 10.82
+	Mm
		925836 LIS1_MOUSE (99-438): 1.81e-49: 179: 14.98		LIS1_MOUSE (140-426): 1.46e-23: 105: 10.82
+	Hs
		792949 LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21
+	Hs
		903418 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60
+	Hs
		1239053 A16L2_HUMAN (487-605): 8.46e-18: 89: 19.33		FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60
+	Hs
		903551 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21
+	Mm
		1207553 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		TAF5_MOUSE (161-427): 2.56e-21: 100: 11.23
+	Hs
		903349 WDR5B_HUMAN (165-393): 1.21e-20: 95.1: 11.72		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21
+	Hs
		903077 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21