HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	30196744, 29634390
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 488
+	Hs
		1038460 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1270370 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		936414 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		HDAC2_MOUSE (1-488): 0: 704: 99.39
+	Hs
		903404 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Dm
		1182201 EBI_DROME (163-478): 2.44e-58: 209: 15.93		Q7KTS4_DROME (10-430): 0: 560: 57.11
+	Dm
		1279322 EBI_DROME (163-478): 2.44e-58: 209: 15.93		Q9VNC2_DROME (10-430): 0: 556: 56.88
+	Mm
		140299 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		903202 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177249 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		921762 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		921074 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1334921 GBB4_HUMAN (165-516): 4.49e-42: 156: 16.07		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04