HitPredict

Interactor 1: FTM (Q68CZ1)
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)
Gene: RPGRIP1L

Interactor 2: NEK1 (Q96PY6)
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)
Gene: NEK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1315 Hs			1 1258
+	Mm
		936580 FTM_MOUSE (1-1315): 0: 775: 81.99		ROCK1_MOUSE (2-1044): 1.58e-141: 466: 15.52
+	Hs
		851541 FTM_HUMAN (1-1315): 0: 899: 100.00		NEK4_HUMAN (1-266): 1.31e-78: 279: 50.56
+	Hs
		851637 RPGR1_HUMAN (253-1313): 0: 631: 31.62		NEK4_HUMAN (1-266): 1.31e-78: 279: 50.56
+	Hs
		149126 MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Rn
		92843 CTRO_RAT (31-796): 9.82e-36: 150: 11.99		ROCK2_RAT (2-1006): 3.76e-135: 449: 17.01
+	Hs
		148126 CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		1268126 MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03		MRCKB_HUMAN (2-924): 7.79e-131: 442: 17.13
+	Hs
		1268074 MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03		MARK4_HUMAN (3-644): 2.23e-138: 441: 16.56
+	Hs
		148460 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		148466 MYH11_HUMAN (331-785): 6.23e-15: 82.5: 12.72		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Bt
		1100183 ROCK2_BOVIN (245-762): 5.71e-20: 99.1: 11.28		ROCK2_BOVIN (2-1006): 1.17e-140: 464: 17.11
+	Hs
		724810 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		ROCK1_HUMAN (2-1044): 4.42e-142: 467: 15.73
+	Hs
		724967 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		MARK4_HUMAN (3-644): 2.23e-138: 441: 16.56
+	Hs
		725010 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		SIK2_HUMAN (4-781): 8.83e-134: 434: 15.15
+	Hs
		728513 MYH11_HUMAN (331-785): 6.23e-15: 82.5: 12.72		SIK2_HUMAN (4-781): 8.83e-134: 434: 15.15
+	Hs
		681696 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		AKT1_HUMAN (1-316): 5.31e-119: 380: 27.41
+	Hs
		851391 NEK4_HUMAN (995-1144): 1.38e-28: 126: 34.84		NEK4_HUMAN (1-266): 1.31e-78: 279: 50.56
+	Hs
		724727 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		NEK4_HUMAN (1-266): 1.31e-78: 279: 50.56
+	Hs
		724726 MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48		NEK2_HUMAN (2-259): 6.99e-51: 188: 42.32