HitPredict

Interactor 1: MSL1 (Q68DK7)
Male-specific lethal 1 homolog (MSL-1) (Male-specific lethal 1-like 1) (MSL1-like 1) (Male-specific lethal-1 homolog 1)
Gene: MSL1

Interactor 2: MSL2 (Q9HCI7)
E3 ubiquitin-protein ligase MSL2 (EC 2.3.2.27) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184)
Gene: MSL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 28514442, 33961781, 24981860, 16227571, 23084835
Identification Methods affinity chromatography technology, x-ray crystallography, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MSL1_dimer~zf-RING_10
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045893 - positive regulation of DNA-templated transcription
GO:0072487 - MSL complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 614
Hs

1 577
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024