HitPredict

Interactor 1: RNF43 (Q68DV7)
E3 ubiquitin-protein ligase RNF43 (EC 2.3.2.27) (RING finger protein 43) (RING-type E3 ubiquitin transferase RNF43)
Gene: RNF43

Interactor 2: RNF43 (Q68DV7)
E3 ubiquitin-protein ligase RNF43 (EC 2.3.2.27) (RING finger protein 43) (RING-type E3 ubiquitin transferase RNF43)
Gene: RNF43

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 18313049, 37011906
Identification Methods enzymatic study, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_2~zf-RING_2, ZNRF_3_ecto~ZNRF_3_ecto
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005109 - frizzled binding
GO:0005635 - nuclear envelope
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
and 8 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 783
Hs

1 783
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024