Interactor 1: LHX8 (Q68G74)
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Gene: LHX8

Interactor 2: FIGLA (Q6QHK4)
Factor in the germline alpha (FIGalpha) (Class C basic helix-loop-helix protein 8) (bHLHc8) (Folliculogenesis-specific basic helix-loop-helix protein) (Transcription factor FIGa)
Gene: FIGLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 32296183, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~LIM
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 356
Hs

1 219
+ Hs
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+ Mm
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+ Dm

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Last updated: 15 Jul 2024