HitPredict

Interactor 1: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Interactor 2: CCHCR (Q8TD31)
Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8)
Gene: CCHCR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	25416956, 29892012, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 431 Hs			1 782
+	Hs
		280665 KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		444434 K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		445093 K1C16_HUMAN (85-412): 2.56e-96: 298: 51.52		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		580076 K1C15_HUMAN (88-401): 4.65e-95: 295: 52.38		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		49575 A1A4E9_HUMAN (80-411): 7.5e-95: 294: 50.75		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		531499 K1C13_HUMAN (80-411): 1.72e-94: 293: 50.75		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		318847 K2C75_HUMAN (2-414): 4.39e-87: 277: 24.88		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		1254462 KRT35_HUMAN (2-427): 4.45e-87: 274: 59.35		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		444487 K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90		MYO5C_HUMAN (90-633): 2e-50: 194: 20.00
+	Hs
		64599 K1C39_HUMAN (2-430): 3.23e-153: 444: 50.11		MYH7B_HUMAN (16-319): 7.31e-09: 61.6: 10.49
+	Hs
		280817 KRT36_HUMAN (7-407): 2.14e-84: 267: 63.34		CCHCR_HUMAN (1-782): 4.29e-66: 236: 100.00
+	Hs
		49550 A1A4E9_HUMAN (80-411): 7.5e-95: 294: 50.75		MYH1_HUMAN (14-726): 3.24e-29: 127: 11.25
+	Hs
		522534 K1C13_HUMAN (80-411): 1.72e-94: 293: 50.75		MYH1_HUMAN (14-726): 3.24e-29: 127: 11.25
+	Hs
		522555 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH1_HUMAN (14-726): 3.24e-29: 127: 11.25
+	Hs
		444436 K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90		RBCC1_HUMAN (158-735): 1.98e-09: 63.7: 20.23
+	Hs
		724787 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH9_HUMAN (425-782): 5.72e-11: 68.5: 14.09
+	Hs
		725143 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH10_HUMAN (425-782): 7.32e-11: 68.1: 13.81
+	Hs
		980293 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		RBCC1_HUMAN (158-735): 1.98e-09: 63.7: 20.23
+	Hs
		502919 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH3_HUMAN (253-781): 7.56e-19: 94.3: 13.62
+	Hs
		522624 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH7_HUMAN (18-474): 1.67e-15: 83.5: 9.19