HitPredict

Interactor 1: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 431 Hs			1 335
+	Hs
		280539 KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		359311 K1C14_HUMAN (87-400): 4.31e-146: 425: 53.82		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		280491 KT33A_HUMAN (26-429): 3.98e-112: 337: 60.15		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787911 KT33B_HUMAN (23-429): 5.43e-111: 333: 58.48		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787899 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		445014 K1C16_HUMAN (85-412): 2.56e-96: 298: 51.52		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		724787 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		787940 K2C73_HUMAN (3-403): 6.76e-91: 287: 23.34		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787892 KRT83_HUMAN (3-426): 3.19e-91: 286: 27.36		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		49550 A1A4E9_HUMAN (80-411): 7.5e-95: 294: 50.75		MYH1_HUMAN (3-226): 1.26e-35: 139: 13.84
+	Hs
		522534 K1C13_HUMAN (80-411): 1.72e-94: 293: 50.75		MYH1_HUMAN (3-226): 1.26e-35: 139: 13.84
+	Hs
		213932 KRT86_HUMAN (4-428): 1.35e-89: 282: 27.75		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787893 KRT85_HUMAN (1-428): 1.82e-88: 279: 26.62		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		318787 K2C75_HUMAN (2-414): 4.39e-87: 277: 24.88		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787956 KRT35_HUMAN (2-427): 4.45e-87: 274: 59.35		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		725143 K1C17_HUMAN (82-401): 2.06e-100: 307: 52.81		MYH10_HUMAN (2-205): 2.43e-27: 115: 20.10
+	Hs
		280780 KRT36_HUMAN (7-407): 2.14e-84: 267: 63.34		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787928 K2C79_HUMAN (3-420): 1.24e-83: 267: 23.06		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		787912 K1H2_HUMAN (1-426): 1.69e-83: 265: 55.63		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		502919 K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00		MYH3_HUMAN (3-235): 1.67e-33: 133: 12.88