HitPredict

Interactor 1: SL9A4 (Q6AI14)
Sodium/hydrogen exchanger 4 (Na(+)/H(+) exchanger 4) (NHE-4) (Solute carrier family 9 member 4)
Gene: SLC9A4

Interactor 2: CHP1 (Q99653)
Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)
Gene: CHP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12576672
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	EF-hand_7~NEXCaM_BD
Common GO terms	GO:0005886 - plasma membrane GO:0015385 - sodium:proton antiporter activity GO:0051453 - regulation of intracellular pH
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 798 Hs			1 195
+	Hs
		212570 SL9A4_HUMAN (1-798): 0: 891: 100.00		CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03
+	Rn
		642818 SL9A4_RAT (1-681): 0: 716: 87.37		CHP1_RAT (1-195): 5.21e-50: 162: 98.97
+	Rn
		642819 SL9A4_RAT (1-681): 0: 716: 87.37		CHP2_RAT (1-194): 8.61e-45: 149: 61.03
+	Rn
		822754 SL9A2_RAT (23-698): 0: 666: 61.84		CHP1_RAT (1-195): 5.21e-50: 162: 98.97
+	Rn
		822755 SL9A2_RAT (23-698): 0: 666: 61.84		CHP2_RAT (1-194): 8.61e-45: 149: 61.03
+	Hs
		1305458 SL9A2_HUMAN (23-698): 0: 628: 60.97		CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00
+	Hs
		212574 SL9A2_HUMAN (23-698): 0: 628: 60.97		CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03
+	Hs
		586063 SL9A1_HUMAN (21-676): 0: 565: 43.63		CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00
+	Hs
		212564 SL9A1_HUMAN (21-676): 0: 565: 43.63		CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03
+	Hs
		586058 SL9A1_HUMAN (21-676): 0: 565: 43.63		CHP3_HUMAN (1-195): 1.08e-46: 154: 33.33
+	Rn
		642812 SL9A1_RAT (21-676): 0: 549: 43.29		CHP1_RAT (1-195): 5.21e-50: 162: 98.97
+	Rn
		642815 SL9A3_RAT (41-672): 1.32e-179: 538: 39.59		CHP1_RAT (1-195): 5.21e-50: 162: 98.97
+	Hs
		822764 SL9A3_HUMAN (56-672): 4.1e-179: 537: 40.21		CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00
+	Rn
		642813 SL9A1_RAT (21-676): 0: 549: 43.29		CHP2_RAT (1-194): 8.61e-45: 149: 61.03
+	Hs
		212565 SL9A3_HUMAN (56-672): 4.1e-179: 537: 40.21		CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03
+	Rn
		642816 SL9A3_RAT (41-672): 1.32e-179: 538: 39.59		CHP2_RAT (1-194): 8.61e-45: 149: 61.03
+	Hs
		1060400 SL9A5_HUMAN (57-680): 6.39e-166: 505: 40.00		CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00
+	Hs
		212568 SL9A5_HUMAN (57-680): 6.39e-166: 505: 40.00		CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03
+	Rn
		895408 SL9A5_RAT (38-680): 9.34e-163: 496: 38.97		CHP1_RAT (1-195): 5.21e-50: 162: 98.97
+	Rn
		1194995 SL9A5_RAT (38-680): 9.34e-163: 496: 38.97		CHP2_RAT (1-194): 8.61e-45: 149: 61.03