HitPredict

Interactor 1: PDLI2 (Q6AYD6)
PDZ and LIM domain protein 2
Gene: Pdlim2

Interactor 2: ACTN4 (Q9QXQ0)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15505042
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0030018 - Z disc GO:0030036 - actin cytoskeleton organization GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 349 Rn			1 911
+	Rn
		1149817 PDLI2_RAT (1-349): 1.66e-67: 217: 100.00		ACTN1_RAT (23-911): 0: 612: 85.94
+	Hs
		117245 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN1_HUMAN (23-911): 0: 611: 85.71
+	Hs
		521502 PDLI4_HUMAN (1-342): 6.53e-51: 174: 29.45		ACTN1_HUMAN (23-911): 0: 611: 85.71
+	Hs
		117234 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN4_HUMAN (1-911): 0: 593: 98.46
+	Hs
		117270 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN3_HUMAN (37-911): 0: 571: 74.17
+	Hs
		117257 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN2_HUMAN (26-911): 0: 568: 77.20
+	Hs
		725662 PDLI3_HUMAN (1-342): 7.59e-51: 175: 28.89		ACTN2_HUMAN (26-911): 0: 568: 77.20
+	Hs
		521616 SYP2L_HUMAN (5-275): 1.12e-26: 113: 20.98		ACTN1_HUMAN (23-911): 0: 611: 85.71
+	Dm
		574823 Q95TZ7_DROME (12-222): 1.03e-37: 141: 21.80		ACTN_DROME (28-911): 0: 574: 67.14
+	Ce
		104996 G5EC72_CAEEL (12-338): 1.4e-49: 173: 18.60		Q23158_CAEEL (11-907): 4.77e-174: 530: 59.57
+	Mm
		49891 DLG4_MOUSE (8-86): 7.84e-19: 89.5: 27.06		A1BN54_MOUSE (23-911): 0: 597: 84.03
+	Hs
		725714 SYNP2_HUMAN (5-301): 3.83e-28: 117: 15.15		ACTN2_HUMAN (26-911): 0: 568: 77.20
+	Hs
		993296 SYP2L_HUMAN (5-275): 1.12e-26: 113: 20.98		ACTN3_HUMAN (37-911): 0: 571: 74.17
+	Hs
		725700 SYP2L_HUMAN (5-275): 1.12e-26: 113: 20.98		ACTN2_HUMAN (26-911): 0: 568: 77.20
+	Mm
		885081 DLG4_MOUSE (8-86): 7.84e-19: 89.5: 27.06		ACTN4_MOUSE (1-911): 0: 584: 98.68
+	Mm
		1337461 LDB3_MOUSE (80-346): 2.28e-19: 91.3: 10.83		ACTN2_MOUSE (26-911): 0: 571: 77.54
+	Hs
		725643 DLG4_HUMAN (8-86): 7.84e-19: 89.5: 27.06		ACTN2_HUMAN (26-911): 0: 568: 77.20
+	Ce
		103987 G5EC72_CAEEL (12-338): 1.4e-49: 173: 18.60		G5EBH3_CAEEL (392-782): 8.23e-09: 62: 15.65
+	Mm
		57232 A2AKD7_MOUSE (4-270): 1.98e-29: 119: 16.43		SPTB1_MOUSE (227-782): 1.9e-10: 67.4: 11.65
+	Mm
		1143324 DLG4_MOUSE (8-86): 7.84e-19: 89.5: 27.06		SPTB2_MOUSE (262-836): 6.62e-09: 62: 12.61