HitPredict

Interactor 1: PDLI2 (Q6AYD6)
PDZ and LIM domain protein 2
Gene: Pdlim2

Interactor 2: ACTN1 (Q9Z1P2)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15505042
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0030018 - Z disc GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 349 Rn			1 892
+	Hs
		117245 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN1_HUMAN (1-892): 0: 665: 99.33
+	Hs
		521502 PDLI4_HUMAN (1-342): 6.53e-51: 174: 29.45		ACTN1_HUMAN (1-892): 0: 665: 99.33
+	Rn
		1149816 PDLI2_RAT (1-349): 1.66e-67: 217: 100.00		ACTN4_RAT (11-892): 0: 612: 86.62
+	Hs
		117234 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN4_HUMAN (11-892): 0: 615: 86.96
+	Hs
		117270 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN3_HUMAN (18-892): 0: 609: 78.17
+	Hs
		117257 PDLI1_HUMAN (2-342): 2.07e-53: 180: 31.09		ACTN2_HUMAN (10-892): 0: 608: 80.29
+	Hs
		725662 PDLI3_HUMAN (1-342): 7.59e-51: 175: 28.89		ACTN2_HUMAN (10-892): 0: 608: 80.29
+	Hs
		521616 SYP2L_HUMAN (5-275): 1.12e-26: 113: 20.98		ACTN1_HUMAN (1-892): 0: 665: 99.33
+	Dm
		574823 Q95TZ7_DROME (12-222): 1.03e-37: 141: 21.80		ACTN_DROME (2-892): 0: 615: 67.39
+	Mm
		49891 DLG4_MOUSE (8-86): 7.84e-19: 89.5: 27.06		A1BN54_MOUSE (1-892): 0: 651: 97.31
+	Hs
		725714 SYNP2_HUMAN (5-301): 3.83e-28: 117: 15.15		ACTN2_HUMAN (10-892): 0: 608: 80.29
+	Hs
		993296 SYP2L_HUMAN (5-275): 1.12e-26: 113: 20.98		ACTN3_HUMAN (18-892): 0: 609: 78.17
+	Hs
		725700 SYP2L_HUMAN (5-275): 1.12e-26: 113: 20.98		ACTN2_HUMAN (10-892): 0: 608: 80.29
+	Mm
		1337461 LDB3_MOUSE (80-346): 2.28e-19: 91.3: 10.83		ACTN2_MOUSE (10-892): 0: 611: 80.63
+	Mm
		885081 DLG4_MOUSE (8-86): 7.84e-19: 89.5: 27.06		ACTN4_MOUSE (11-892): 0: 611: 86.96
+	Hs
		725643 DLG4_HUMAN (8-86): 7.84e-19: 89.5: 27.06		ACTN2_HUMAN (10-892): 0: 608: 80.29
+	Ce
		103987 G5EC72_CAEEL (12-338): 1.4e-49: 173: 18.60		G5EBH3_CAEEL (155-795): 1.75e-13: 77.3: 11.88
+	Ce
		104996 G5EC72_CAEEL (12-338): 1.4e-49: 173: 18.60		Q23158_CAEEL (143-891): 2.42e-13: 76.2: 13.65
+	Mm
		57232 A2AKD7_MOUSE (4-270): 1.98e-29: 119: 16.43		SPTB1_MOUSE (252-801): 1.04e-10: 68.1: 11.96
+	Mm
		1143324 DLG4_MOUSE (8-86): 7.84e-19: 89.5: 27.06		SPTB2_MOUSE (257-798): 2.61e-14: 79.7: 13.10