HitPredict

Interactor 1: Q6DDX5 (Q6DDX5)
Anapc7-prov protein (Anaphase promoting complex subunit 7 L homeolog)
Gene: anapc7.L

Interactor 2: Q6GQ04 (Q6GQ04)
Cell division cycle protein 27 homolog
Gene: MGC80529

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	16364912, 20951947
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC3~TPR_8, TPR_1~TPR_8, TPR_8~TPR_8
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0016567 - protein ubiquitination GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 565 Xl			1 833
+	Hs
		672917 APC7_HUMAN (1-565): 3.63e-105: 329: 93.81		CDC27_HUMAN (1-833): 0: 553: 89.33
+	Mm
		56872 APC7_MOUSE (1-565): 2e-101: 319: 92.92		CDC27_MOUSE (1-833): 0: 549: 88.85
+	Hs
		672772 CDC27_HUMAN (23-551): 1.06e-67: 236: 18.70		CDC27_HUMAN (1-833): 0: 553: 89.33
+	Hs
		175291 APC7_HUMAN (1-565): 3.63e-105: 329: 93.81		OGT1_HUMAN (323-801): 9.48e-76: 268: 13.15
+	Hs
		1356132 APC7_HUMAN (1-565): 3.63e-105: 329: 93.81		APC7_HUMAN (309-822): 2.98e-65: 230: 15.92
+	Hs
		1356109 APC7_HUMAN (1-565): 3.63e-105: 329: 93.81		CDC23_HUMAN (368-800): 1.01e-32: 136: 14.94
+	Hs
		672848 CDC27_HUMAN (23-551): 1.06e-67: 236: 18.70		Q5T8C6_HUMAN (488-804): 3.05e-57: 205: 19.00
+	Hs
		1023016 APC7_HUMAN (1-565): 3.63e-105: 329: 93.81		CDC16_HUMAN (371-830): 6.86e-13: 74.2: 10.83
+	Hs
		1022909 Q4KMX6_HUMAN (2-565): 2.04e-104: 327: 93.79		CDC16_HUMAN (371-830): 6.86e-13: 74.2: 10.83
+	Hs
		672916 CDC27_HUMAN (23-551): 1.06e-67: 236: 18.70		CDC23_HUMAN (368-800): 1.01e-32: 136: 14.94
+	At
		989582 APC7_ARATH (5-545): 6.43e-65: 223: 26.83		CD27A_ARATH (541-825): 2.78e-28: 123: 18.88
+	At
		1228162 APC7_ARATH (5-545): 6.43e-65: 223: 26.83		CD27B_ARATH (574-831): 7.18e-24: 109: 11.28
+	At
		71745 APC7_ARATH (5-545): 6.43e-65: 223: 26.83		CDC16_ARATH (494-833): 1.92e-21: 101: 13.10
+	At
		71743 CDC16_ARATH (3-520): 4.71e-60: 209: 17.72		CD27B_ARATH (574-831): 7.18e-24: 109: 11.28
+	At
		1257915 APC7_ARATH (5-545): 6.43e-65: 223: 26.83		CDC23_ARATH (533-829): 1.67e-18: 91.9: 12.46
+	Hs
		672822 CDC27_HUMAN (23-551): 1.06e-67: 236: 18.70		CDC16_HUMAN (371-830): 6.86e-13: 74.2: 10.83
+	At
		71751 CDC16_ARATH (3-520): 4.71e-60: 209: 17.72		CDC23_ARATH (533-829): 1.67e-18: 91.9: 12.46
+	Sp
		293621 CUT9_SCHPO (9-521): 1.97e-53: 194: 13.71		APC8_SCHPO (446-651): 2.53e-12: 72.3: 12.74