HitPredict

Interactor 1: Q6DFI7 (Q6DFI7)
Cdc16-prov protein (Cell division cycle 16 L homeolog)
Gene: cdc16.L

Interactor 2: Q6GQ04 (Q6GQ04)
Cell division cycle protein 27 homolog
Gene: MGC80529

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	16364912, 20951947
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC3~ANAPC3, ANAPC3~TPR_8, ANAPC3~TPR_12, TPR_1~TPR_12, TPR_12~TPR_8
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 621 Xl			1 833
+	Hs
		672822 CDC16_HUMAN (1-621): 5.4e-113: 352: 88.60		CDC27_HUMAN (1-833): 0: 553: 89.33
+	Hs
		672848 Q5T8C6_HUMAN (95-621): 6.84e-71: 238: 71.65		CDC27_HUMAN (1-833): 0: 553: 89.33
+	Hs
		672917 APC7_HUMAN (10-538): 2.44e-68: 234: 14.95		CDC27_HUMAN (1-833): 0: 553: 89.33
+	Hs
		1022909 CDC16_HUMAN (1-621): 5.4e-113: 352: 88.60		Q4KMX6_HUMAN (309-822): 3.1e-65: 230: 15.92
+	Hs
		1023016 CDC16_HUMAN (1-621): 5.4e-113: 352: 88.60		APC7_HUMAN (309-822): 2.98e-65: 230: 15.92
+	Sc
		454909 CDC16_YEAST (3-575): 8.64e-71: 246: 29.57		CDC27_YEAST (2-717): 1.03e-75: 263: 16.51
+	Sc
		561118 CDC23_YEAST (39-499): 7.22e-72: 245: 15.49		CDC27_YEAST (2-717): 1.03e-75: 263: 16.51
+	Mm
		1186529 NPHP3_MOUSE (143-608): 2.67e-66: 237: 16.70		OGT1_MOUSE (323-801): 7.5e-76: 269: 13.15
+	Hs
		175291 APC7_HUMAN (10-538): 2.44e-68: 234: 14.95		OGT1_HUMAN (323-801): 9.48e-76: 268: 13.15
+	Hs
		1023015 CDC16_HUMAN (1-621): 5.4e-113: 352: 88.60		CDC23_HUMAN (368-800): 1.01e-32: 136: 14.94
+	Sc
		454883 CDC16_YEAST (3-575): 8.64e-71: 246: 29.57		CDC16_YEAST (498-781): 6.49e-44: 173: 18.43
+	Sc
		454891 CDC16_YEAST (3-575): 8.64e-71: 246: 29.57		CDC23_YEAST (415-806): 3.82e-29: 125: 13.27
+	Hs
		1356109 APC7_HUMAN (10-538): 2.44e-68: 234: 14.95		CDC23_HUMAN (368-800): 1.01e-32: 136: 14.94
+	Sc
		561105 CDC23_YEAST (39-499): 7.22e-72: 245: 15.49		CDC23_YEAST (415-806): 3.82e-29: 125: 13.27
+	At
		989582 APC7_ARATH (3-539): 2.03e-73: 247: 15.59		CD27A_ARATH (541-825): 2.78e-28: 123: 18.88
+	At
		1228162 APC7_ARATH (3-539): 2.03e-73: 247: 15.59		CD27B_ARATH (574-831): 7.18e-24: 109: 11.28
+	At
		71745 APC7_ARATH (3-539): 2.03e-73: 247: 15.59		CDC16_ARATH (494-833): 1.92e-21: 101: 13.10
+	At
		1257915 APC7_ARATH (3-539): 2.03e-73: 247: 15.59		CDC23_ARATH (533-829): 1.67e-18: 91.9: 12.46