HitPredict

Interactor 1: SMCA2 (Q6DIC0)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: Smarca2

Interactor 2: CREST (Q8BW22)
Calcium-responsive transactivator (SS18-like protein 1)
Gene: Ss18l1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19279220
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0071565 - nBAF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1577 Mm			1 402
+	Hs
		257458 SMCA2_HUMAN (1-1577): 0: 1051: 93.82		CREST_HUMAN (1-402): 3.9e-84: 263: 89.80
+	Hs
		846783 SMCA2_HUMAN (1-1577): 0: 1051: 93.82		SSXT_HUMAN (1-402): 1.05e-73: 237: 55.50
+	Mm
		1111948 SMCA4_MOUSE (1-1575): 0: 999: 73.58		CREST_MOUSE (1-402): 1.39e-90: 280: 100.00
+	Hs
		60100 SMCA2_HUMAN (1-1577): 0: 1051: 93.82		A4PIW0_HUMAN (1-334): 1.74e-61: 206: 50.72
+	Hs
		257459 SMCA4_HUMAN (1-1575): 0: 985: 72.61		CREST_HUMAN (1-402): 3.9e-84: 263: 89.80
+	Mm
		1111934 SMCA4_MOUSE (1-1575): 0: 999: 73.58		SSXT_MOUSE (1-402): 3.72e-77: 246: 61.24
+	Rn
		88986 SMCA4_RAT (1-1575): 0: 1000: 73.64		D4ABC5_RAT (1-402): 1.1e-74: 240: 56.70
+	Mm
		57185 SMCA4_MOUSE (1-1575): 0: 999: 73.58		CHD7_MOUSE (51-389): 1.71e-64: 225: 17.37
+	Hs
		846980 SMCA4_HUMAN (1-1575): 0: 985: 72.61		SSXT_HUMAN (1-402): 1.05e-73: 237: 55.50
+	Hs
		60089 SMCA4_HUMAN (1-1575): 0: 985: 72.61		A4PIV7_HUMAN (1-394): 1.7e-68: 226: 54.63
+	Hs
		60096 SMCA4_HUMAN (1-1575): 0: 985: 72.61		A4PIV9_HUMAN (1-394): 1.6e-68: 226: 54.63
+	Hs
		846890 SMCA2_HUMAN (1-1577): 0: 1051: 93.82		S18L2_HUMAN (1-73): 1.37e-41: 142: 58.90
+	Mm
		1111937 SMCA2_MOUSE (1-1577): 0: 1084: 100.00		SMCA4_MOUSE (89-393): 1.79e-10: 65.1: 13.64
+	Hs
		847108 SMCA4_HUMAN (1-1575): 0: 985: 72.61		S18L2_HUMAN (1-73): 1.37e-41: 142: 58.90
+	Hs
		846723 SMCA2_HUMAN (1-1577): 0: 1051: 93.82		SMCA4_HUMAN (89-393): 4.88e-10: 63.6: 13.33
+	Mm
		1111917 SMCA4_MOUSE (1-1575): 0: 999: 73.58		SMCA4_MOUSE (89-393): 1.79e-10: 65.1: 13.64
+	Hs
		846899 SMCA4_HUMAN (1-1575): 0: 985: 72.61		SMCA4_HUMAN (89-393): 4.88e-10: 63.6: 13.33
+	Hs
		847103 SMCA4_HUMAN (1-1575): 0: 985: 72.61		CHD7_HUMAN (70-391): 9.07e-10: 62.8: 11.68
+	Hs
		229409 SMCA5_HUMAN (589-1562): 0: 793: 26.67		SSXT_HUMAN (1-402): 1.05e-73: 237: 55.50
+	Hs
		60097 SMCA5_HUMAN (589-1562): 0: 793: 26.67		A4PIW0_HUMAN (1-334): 1.74e-61: 206: 50.72