HitPredict

Interactor 1: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 463
+	Hs
		470613 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		1216283 H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		555695 H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		470615 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Hs
		555699 H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Sc
		392614 H2A2_YEAST (16-128): 5.91e-59: 179: 80.53		RUVB2_YEAST (7-451): 0: 650: 68.76
+	Sc
		392228 H2A1_YEAST (16-127): 2.97e-53: 165: 81.25		RUVB2_YEAST (7-451): 0: 650: 68.76
+	Sc
		392553 H2A2_YEAST (16-128): 5.91e-59: 179: 80.53		RUVB1_YEAST (12-451): 0: 605: 41.72
+	Sc
		392191 H2A1_YEAST (16-127): 2.97e-53: 165: 81.25		RUVB1_YEAST (12-451): 0: 605: 41.72