HitPredict

Interactor 1: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106, Histone_H2A_C~Rtt106
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 1047
+	Hs
		1185216 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		391984 H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		470626 H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1087145 H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1312248 H2AJ_HUMAN (1-128): 2.61e-64: 193: 94.53		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		555708 H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Mm
		650195 H2AX_MOUSE (1-129): 1.01e-62: 189: 90.70		SP16H_MOUSE (1-1047): 0: 1332: 98.66
+	Sc
		392353 H2A2_YEAST (16-128): 5.91e-59: 179: 80.53		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Sc
		392084 H2A1_YEAST (16-127): 2.97e-53: 165: 81.25		SPT16_YEAST (3-1008): 0: 938: 33.49