HitPredict

Interactor 1: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Interactor 2: U3KQK0 (U3KQK0)
Histone H2B
Gene: H2BC15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 166
+	Hs
		1087194 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B2E_HUMAN (1-126): 3.12e-58: 179: 98.41
+	Hs
		1087320 H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46		H2B2E_HUMAN (1-126): 3.12e-58: 179: 98.41
+	Hs
		1151365 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1H_HUMAN (1-126): 3.64e-58: 179: 98.41
+	Hs
		420844 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1J_HUMAN (1-126): 3.68e-58: 179: 97.62
+	Hs
		617952 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1O_HUMAN (1-126): 2.74e-58: 179: 97.62
+	Hs
		918440 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1C_HUMAN (1-126): 4.48e-58: 179: 99.21
+	Hs
		918580 H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46		H2B1C_HUMAN (1-126): 4.48e-58: 179: 99.21
+	Hs
		1087218 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		H2B2E_HUMAN (1-126): 3.12e-58: 179: 98.41
+	Hs
		1151376 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1N_HUMAN (1-126): 1.1e-57: 178: 100.00
+	Hs
		241559 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41
+	Hs
		241601 H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41
+	Hs
		707657 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1B_HUMAN (1-126): 8e-58: 178: 98.41
+	Hs
		886132 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1D_HUMAN (1-126): 1.09e-57: 178: 99.21
+	Hs
		918471 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		H2B1C_HUMAN (1-126): 4.48e-58: 179: 99.21
+	Hs
		241571 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41
+	Hs
		886144 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		H2B1D_HUMAN (1-126): 1.09e-57: 178: 99.21
+	Hs
		1151377 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B1L_HUMAN (1-126): 1.5e-56: 175: 97.62
+	Hs
		1185209 H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69		H2B1L_HUMAN (1-126): 1.5e-56: 175: 97.62
+	Hs
		1151355 H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00		H2B3B_HUMAN (1-126): 1.39e-55: 172: 96.03
+	Hs
		1274382 H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46		H2B1A_HUMAN (1-126): 1.49e-49: 157: 85.83