HitPredict

Interactor 1: M9PEF7 (M9PEF7)
Puratrophin-1-like, isoform D
Gene: Pura

Interactor 2: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGEF
Common GO terms	GO:0048812 - neuron projection morphogenesis GO:1904059 - regulation of locomotor rhythm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1898 Dm			1 192
+	Hs
		166482 MCF2L_HUMAN (670-1816): 2.97e-163: 532: 18.65		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		166478 MCF2L_HUMAN (670-1816): 2.97e-163: 532: 18.65		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		166479 MCF2L_HUMAN (670-1816): 2.97e-163: 532: 18.65		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		894327 PKH4B_HUMAN (583-1729): 6.68e-150: 507: 26.55		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		500934 MCF2_HUMAN (865-1730): 7.13e-149: 486: 19.58		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		500931 MCF2_HUMAN (865-1730): 7.13e-149: 486: 19.58		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		500932 MCF2_HUMAN (865-1730): 7.13e-149: 486: 19.58		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		925330 PKHG4_HUMAN (840-1757): 9.97e-131: 443: 30.53		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		545418 PKHG4_HUMAN (840-1757): 9.97e-131: 443: 30.53		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		892408 PKHG4_HUMAN (840-1757): 9.97e-131: 443: 30.53		RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53
+	Hs
		894092 PKHG4_HUMAN (840-1757): 9.97e-131: 443: 30.53		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		900546 PKHG4_HUMAN (840-1757): 9.97e-131: 443: 30.53		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		925461 ARH40_HUMAN (875-1787): 3.64e-110: 389: 24.10		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		545519 ARH40_HUMAN (875-1787): 3.64e-110: 389: 24.10		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		892502 ARH40_HUMAN (875-1787): 3.64e-110: 389: 24.10		RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53
+	Hs
		894243 ARH40_HUMAN (875-1787): 3.64e-110: 389: 24.10		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		545718 FARP1_HUMAN (923-1751): 3.45e-108: 374: 13.13		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		892698 FARP1_HUMAN (923-1751): 3.45e-108: 374: 13.13		RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53
+	Hs
		564756 FARP1_HUMAN (923-1751): 3.45e-108: 374: 13.13		RHOQ_HUMAN (4-192): 9.76e-73: 220: 62.05
+	Hs
		436587 FARP1_HUMAN (923-1751): 3.45e-108: 374: 13.13		RHOC_HUMAN (5-192): 2.38e-72: 218: 54.26