Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 34079125, 22980980, 25561175
Identification Methods proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001558 - regulation of cell growth
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0031669 - cellular response to nutrient levels
GO:0032008 - positive regulation of TOR signaling
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 161
Hs

1 1335
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024