Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Interactor 2: LTOR3 (Q9UHA4)
Ragulator complex protein LAMTOR3 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3) (MEK-binding partner 1) (Mp1) (Mitogen-activated protein kinase kinase 1-interacting protein 1) (Mitogen-activated protein kinase scaffold protein 1)
Gene: LAMTOR3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 33961781, 34349018, 25561175, 22980980
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LAMTOR~MAPKK1_Int
Common GO terms GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0008104 - protein localization
GO:0031902 - late endosome membrane
GO:0032008 - positive regulation of TOR signaling
and 8 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 161
Hs

1 124
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024