HitPredict

Interactor 1: DESI1 (Q6ICB0)
Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Palmitoyl protein thioesterase DESI1) (EC 3.1.2.22) (Polyubiquitinated substrate transporter) (POST) (S-depalmitoylase DESI1)
Gene: DESI1

Interactor 2: UBQL4 (Q9NRR5)
Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75)
Gene: UBQLN4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29666234
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032434 - regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 168 Hs			1 601
+	Hs
		1152463 DESI1_HUMAN (1-168): 1.21e-79: 235: 100.00		UBQL1_HUMAN (11-601): 1.16e-127: 389: 59.16
+	Hs
		1152462 DESI1_HUMAN (1-168): 1.21e-79: 235: 100.00		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Hs
		803582 DESI1_HUMAN (1-168): 1.21e-79: 235: 100.00		BAG6_HUMAN (2-547): 7.28e-64: 229: 13.41
+	Hs
		1152449 DESI1_HUMAN (1-168): 1.21e-79: 235: 100.00		UBQLN_HUMAN (14-459): 2.04e-60: 210: 29.39
+	Hs
		924325 DESI1_HUMAN (1-168): 1.21e-79: 235: 100.00		RL40_HUMAN (13-103): 6.24e-34: 127: 28.26
+	At
		1092315 Q9SFT9_ARATH (7-167): 1.86e-68: 210: 44.85		UBQ3_ARATH (9-88): 1.35e-32: 129: 30.86
+	Hs
		924035 DESI1_HUMAN (1-168): 1.21e-79: 235: 100.00		RS27A_HUMAN (13-99): 1.11e-12: 68.1: 29.55