HitPredict

Interactor 1: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~PH
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1121 Hs			1 1025
+	Hs
		1153376 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		1153251 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		724876 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		1334839 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		1334863 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		PKHA6_HUMAN (356-581): 1.69e-31: 135: 24.49
+	Ce
		86389 C1P633_CAEEL (7-464): 1.13e-46: 184: 11.64		G5EE23_CAEEL (7-905): 8.12e-62: 230: 14.65
+	Hs
		1281529 CYH2_HUMAN (105-300): 1.31e-44: 168: 21.50		CNKR1_HUMAN (351-693): 2.42e-66: 239: 21.04
+	Ce
		86408 C1P635_CAEEL (7-464): 1.64e-44: 177: 11.64		G5EE23_CAEEL (7-905): 8.12e-62: 230: 14.65
+	Hs
		1074109 CYH1_HUMAN (105-281): 4.55e-43: 164: 21.69		CNKR1_HUMAN (351-693): 2.42e-66: 239: 21.04
+	Hs
		1281534 CYH4_HUMAN (95-286): 8.79e-43: 163: 20.98		CNKR1_HUMAN (351-693): 2.42e-66: 239: 21.04
+	Hs
		1068669 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		876450 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		148941 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		149443 PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		876417 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		876505 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		1231295 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		OSBP2_HUMAN (273-623): 1.26e-32: 138: 15.11
+	Hs
		724914 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		725200 RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18