HitPredict

Interactor 1: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Interactor 2: THOC6 (Q86W42)
THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)
Gene: THOC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1121 Hs			1 341
+	Hs
		920990 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		GBB1_HUMAN (117-339): 5.07e-23: 99.7: 12.04
+	Hs
		1153322 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		FBXW7_HUMAN (1-149): 4.03e-22: 99.3: 7.38
+	Hs
		903302 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		1153371 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		TBL1R_HUMAN (205-336): 4.01e-12: 69: 10.60
+	Hs
		1240465 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		POC1A_HUMAN (114-338): 1.1e-57: 193: 13.54
+	Hs
		1202883 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		THOC6_HUMAN (1-341): 3.26e-82: 254: 100.00
+	Hs
		793030 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		LIS1_HUMAN (72-337): 1.89e-70: 226: 9.62
+	Hs
		197087 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		PRP4_HUMAN (2-244): 2.6e-52: 182: 12.65
+	Hs
		236256 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		PRP17_HUMAN (1-284): 9.1e-50: 176: 8.67
+	Hs
		1309164 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		TBL1Y_HUMAN (116-338): 3.12e-39: 147: 13.75
+	Hs
		921057 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		GBB1_HUMAN (117-339): 5.07e-23: 99.7: 12.04
+	Mm
		921099 CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87		GBB1_MOUSE (117-339): 5.07e-23: 99.7: 12.04
+	Hs
		1246481 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		WDR36_HUMAN (18-259): 8.21e-18: 86.4: 17.00
+	Hs
		1288303 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		SNR40_HUMAN (1-152): 5.89e-29: 116: 14.65
+	Hs
		876342 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		921047 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		GBB1_HUMAN (117-339): 5.07e-23: 99.7: 12.04
+	Hs
		125310 WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		1246478 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		WDR36_HUMAN (18-259): 8.21e-18: 86.4: 17.00
+	Hs
		903516 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		267793 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		TAF5L_HUMAN (17-304): 3.75e-12: 69: 20.94