HitPredict

Interactor 1: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1121 Hs			1 530
+	Hs
		369813 PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269656 PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1154059 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269970 PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369815 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370480 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369255 AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		212318 CYH3_HUMAN (160-280): 1.5e-27: 118: 27.64		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369666 CYH1_HUMAN (105-281): 4.55e-43: 164: 21.69		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1056909 MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		782571 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377401 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		369607 MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		611504 SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		377684 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		490117 PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84		COT1_HUMAN (83-502): 2.36e-106: 326: 23.88
+	Hs
		377607 NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487522 NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1336130 SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58		NR2E1_HUMAN (149-408): 2.63e-35: 137: 31.82
+	Hs
		487431 MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59