HitPredict

Interactor 1: KLH10 (Q6JEL2)
Kelch-like protein 10
Gene: KLHL10

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 608 Hs			1 701
+	Hs
		1221252 KLHL7_HUMAN (14-579): 0: 526: 26.70		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1120825 KLH12_HUMAN (19-575): 8.8e-171: 499: 32.32		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1348054 KLH28_HUMAN (372-608): 7.71e-58: 205: 26.19		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350369 KLHL9_HUMAN (387-607): 1.86e-54: 197: 22.81		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350481 KLH13_HUMAN (387-607): 5.12e-53: 194: 21.93		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354637 KLHL3_HUMAN (429-606): 4.63e-47: 176: 33.15		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		307226 KLHL2_HUMAN (435-607): 2.73e-42: 163: 30.64		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1049349 KEAP1_HUMAN (420-608): 6.31e-41: 159: 24.87		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354642 KLH20_HUMAN (269-432): 1.73e-31: 131: 27.44		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164601 KLH17_HUMAN (469-607): 6.82e-28: 120: 25.90		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1121505 KLH26_HUMAN (365-606): 3.77e-26: 115: 13.53		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1327770 KLH25_HUMAN (432-608): 3.02e-26: 115: 17.11		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354646 IPP_HUMAN (481-608): 1.87e-25: 112: 20.59		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164633 KLH24_HUMAN (448-607): 1.58e-21: 100: 18.56		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354639 KLH21_HUMAN (465-606): 1.52e-20: 97.5: 21.53		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1239687 KLH23_HUMAN (341-574): 5.65e-17: 86.3: 29.63		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00