HitPredict

Interactor 1: NIPBL (Q6KC79)
Nipped-B-like protein (Delangin) (SCC2 homolog)
Gene: NIPBL

Interactor 2: LHX3 (Q9UBR4)
LIM/homeobox protein Lhx3 (LIM homeobox protein 3)
Gene: LHX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2804 Hs			1 397
+	Hs
		1243849 KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63		LHX3_HUMAN (1-397): 1.88e-110: 331: 100.00
+	Hs
		152696 KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15		LHX3_HUMAN (1-397): 1.88e-110: 331: 100.00
+	Mm
		292001 MINT_MOUSE (63-894): 1.82e-12: 75.8: 10.85		LMX1B_MOUSE (1-339): 4.48e-65: 214: 28.50
+	Hs
		822650 KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63		LHX1_HUMAN (31-396): 6.18e-62: 206: 32.21
+	Hs
		152612 KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15		LHX1_HUMAN (31-396): 6.18e-62: 206: 32.21
+	Hs
		152657 KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15		LHX8_HUMAN (30-290): 3.86e-49: 171: 29.12
+	Hs
		150606 TITIN_HUMAN (64-830): 1.91e-09: 65.9: 8.36		ABLM1_HUMAN (31-193): 2.42e-25: 110: 22.35
+	Hs
		1151801 TITIN_HUMAN (64-830): 1.91e-09: 65.9: 8.36		ABLM2_HUMAN (10-353): 4.12e-25: 109: 15.83
+	Hs
		839785 KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63		LHX2_HUMAN (136-281): 4.68e-15: 77.9: 23.90
+	Hs
		152615 KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15		LHX2_HUMAN (136-281): 4.68e-15: 77.9: 23.90
+	Hs
		1243832 KMT2C_HUMAN (291-1338): 6.93e-10: 67.5: 8.63		LHX4_HUMAN (8-83): 1.09e-13: 73.9: 25.00
+	Hs
		152677 KMT2D_HUMAN (6-887): 4.25e-09: 64.8: 10.15		LHX4_HUMAN (8-83): 1.09e-13: 73.9: 25.00