Interactor 1: PRR5L (Q6MZQ0)
Proline-rich protein 5-like (Protein observed with Rictor-2) (Protor-2)
Gene: PRR5L

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.725

The method score is based on:

Property Details
Experiments 18030348, 21964062, 35973513, 17461779, 18505677
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, pull down, in-gel kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0031932 - TORC2 complex
GO:0038203 - TORC2 signaling
GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 368
Hs

1 1708
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024