HitPredict

Interactor 1: NEDD8 (Q15843)
Ubiquitin-like protein NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8)
Gene: NEDD8

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22268729
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	F-box-like~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006508 - proteolysis
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 293
+	Hs
		987482 RL40_HUMAN (1-76): 3.81e-33: 112: 57.90		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		507383 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		507414 UBB_HUMAN (1-76): 2.41e-30: 107: 57.90		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1154955 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17