HitPredict

Interactor 1: DWA2 (Q6NPN9)
WD repeat-containing protein DWA2 (Protein DWD HYPERSENSITIVE TO ABA 2)
Gene: DWA2

Interactor 2: CUL4 (Q8LGH4)
Cullin-4 (AtCUL4)
Gene: CUL4

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20525848
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0009738 - abscisic acid-activated signaling pathway GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 At			1 792
+	Hs
		1043509 SNR40_HUMAN (98-350): 4.7e-53: 180: 18.82		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Hs
		1043157 SNR40_HUMAN (98-350): 4.7e-53: 180: 18.82		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		903209 WDR5_HUMAN (4-236): 5.07e-42: 150: 13.69		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Hs
		1043441 WDR5B_HUMAN (5-236): 7.88e-41: 147: 13.33		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Hs
		903208 WDR5_HUMAN (4-236): 5.07e-42: 150: 13.69		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		1043085 WDR5B_HUMAN (5-236): 7.88e-41: 147: 13.33		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	At
		186930 MSI1_ARATH (153-347): 5.02e-28: 114: 15.96		CUL4_ARATH (1-792): 0: 944: 100.00
+	Hs
		997715 RBBP4_HUMAN (4-150): 7.97e-24: 103: 15.13		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Hs
		1043376 RBBP7_HUMAN (5-150): 3.24e-23: 101: 15.23		CUL4B_HUMAN (29-792): 0: 925: 55.95
+	Hs
		792982 LIS1_HUMAN (4-151): 5.85e-24: 103: 12.20		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		997714 RBBP4_HUMAN (4-150): 7.97e-24: 103: 15.13		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		1043016 RBBP7_HUMAN (5-150): 3.24e-23: 101: 15.23		CUL4A_HUMAN (34-792): 0: 915: 55.79
+	Hs
		903207 WDR5_HUMAN (4-236): 5.07e-42: 150: 13.69		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Hs
		197016 PRP4_HUMAN (118-349): 9.72e-39: 146: 11.57		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Hs
		997713 RBBP4_HUMAN (4-150): 7.97e-24: 103: 15.13		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Hs
		1041672 RBBP7_HUMAN (5-150): 3.24e-23: 101: 15.23		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Hs
		725432 COPB2_HUMAN (107-346): 6.07e-18: 87.1: 18.08		CUL3_HUMAN (60-792): 0: 834: 38.63
+	Hs
		903206 WDR5_HUMAN (4-236): 5.07e-42: 150: 13.69		CUL1_HUMAN (93-792): 0: 758: 29.37
+	Ce
		953926 LIN53_CAEEL (207-348): 3.78e-21: 95.6: 20.67		CUL1_CAEEL (80-792): 0: 688: 26.85
+	Ce
		953927 LIN53_CAEEL (207-348): 3.78e-21: 95.6: 20.67		CUL2_CAEEL (63-792): 0: 667: 24.53