HitPredict

Interactor 1: LRC8E (Q6NSJ5)
Volume-regulated anion channel subunit LRRC8E (Leucine-rich repeat-containing protein 8E)
Gene: LRRC8E

Interactor 2: DLK2 (Q6UY11)
Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9)
Gene: DLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 383
+	Hs
		1049987 SCRIB_HUMAN (485-794): 7.75e-69: 250: 28.21		DLK2_HUMAN (1-383): 5.01e-57: 192: 100.00
+	Hs
		1166901 LRC8A_HUMAN (467-796): 1.41e-33: 140: 21.39		DLK2_HUMAN (1-383): 5.01e-57: 192: 100.00
+	Dm
		422829 LAP1_DROME (389-724): 2.92e-50: 192: 22.91		NOTCH_DROME (8-254): 4.99e-15: 78.9: 19.93
+	Dm
		422751 FLII_DROME (698-794): 1.13e-10: 67.7: 24.49		NOTCH_DROME (8-254): 4.99e-15: 78.9: 19.93