HitPredict

Interactor 1: Q6NSK7 (Q6NSK7)
RIN3 protein
Gene: RIN3

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 908 Hs			1 1292
+	Hs
		1251911 RIN3_HUMAN (1-908): 0: 597: 89.04		SRBS1_HUMAN (1-1292): 5.5e-176: 558: 100.00
+	Hs
		537655 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		NCF1_HUMAN (701-1015): 3.76e-50: 185: 17.18
+	Hs
		557717 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		NCK1_HUMAN (708-1005): 1.37e-49: 182: 18.27
+	Hs
		557745 RIN3_HUMAN (1-908): 0: 597: 89.04		NCK1_HUMAN (708-1005): 1.37e-49: 182: 18.27
+	Hs
		70370 RIN3_HUMAN (1-908): 0: 597: 89.04		B2R6S4_HUMAN (708-1005): 1.65e-49: 182: 18.27
+	Hs
		1078842 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		ITSN1_HUMAN (273-858): 7.03e-15: 82.5: 10.91
+	Hs
		1155937 Q6NSK7_HUMAN (1-908): 0: 678: 100.00		ITSN2_HUMAN (1079-1290): 3.39e-12: 73.7: 14.49
+	Hs
		1167810 RIN3_HUMAN (1-908): 0: 597: 89.04		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Hs
		1251932 RIN3_HUMAN (1-908): 0: 597: 89.04		ITSN2_HUMAN (1079-1290): 3.39e-12: 73.7: 14.49
+	Hs
		235552 RIN3_HUMAN (1-908): 0: 597: 89.04		VINEX_HUMAN (852-938): 9.3e-09: 61.9: 27.59
+	Rn
		192744 SYNJ1_RAT (153-642): 1.6e-44: 177: 15.79		SRBS2_RAT (508-926): 5.66e-14: 79.4: 15.40
+	Rn
		193638 SYNJ1_RAT (153-642): 1.6e-44: 177: 15.79		SH3G1_RAT (780-926): 2.11e-14: 78.4: 26.14
+	Hs
		1044770 RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18		ITSN1_HUMAN (273-858): 7.03e-15: 82.5: 10.91
+	Hs
		1044784 RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18		SH3R1_HUMAN (220-850): 8.23e-10: 65.6: 13.22
+	Hs
		235502 RIN1_HUMAN (2-559): 3.8e-37: 152: 20.18		VINEX_HUMAN (852-938): 9.3e-09: 61.9: 27.59
+	Dm
		53003 Q9VHC3_DROME (16-158): 5.13e-29: 126: 21.77		A1Z866_DROME (315-848): 1.58e-12: 74: 11.66
+	Dm
		1197436 Q9VHC3_DROME (16-158): 5.13e-29: 126: 21.77		Q86P80_DROME (319-848): 2.46e-12: 73.3: 11.74
+	Hs
		235523 TENS2_HUMAN (3-217): 4.89e-32: 137: 19.33		VINEX_HUMAN (852-938): 9.3e-09: 61.9: 27.59
+	Ce
		110116 TENSH_CAEEL (55-196): 2.35e-27: 122: 17.88		Q9U2T9_CAEEL (1077-1290): 7.67e-10: 65.6: 12.61
+	Hs
		235595 TENS1_HUMAN (25-213): 2.14e-25: 115: 14.98		VINEX_HUMAN (852-938): 9.3e-09: 61.9: 27.59