HitPredict

Interactor 1: M9PGE1 (M9PGE1)
Dpr-interacting protein alpha, isoform B
Gene: DIP-alpha

Interactor 2: Q9VT83 (Q9VT83)
Defective proboscis extension response 10, isoform A (Defective proboscis extension response 10, isoform B) (Defective proboscis extension response 10, isoform C)
Gene: dpr10

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.920

Property	Details
Experiments	23827685, 26687361, 30467080, 32358559, 30688651
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	I-set~I-set, Ig_3~I-set, Ig_3~Ig_3
Common GO terms	GO:0032589 - neuron projection membrane GO:0050808 - synapse organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 432 Dm			1 408
+	Dm
		115782 M9PGE1_DROME (1-423): 5.72e-87: 273: 100.00		X2J8X8_DROME (34-340): 2.53e-63: 210: 48.90
+	Dm
		1373879 Q9W4R3_DROME (22-364): 7.17e-46: 168: 17.98		Q9VT83_DROME (1-408): 4.34e-90: 280: 100.00
+	Dm
		1373877 Q9W4R3_DROME (22-364): 7.17e-46: 168: 17.98		Q9VT76_DROME (34-308): 1.71e-60: 199: 48.73
+	Dm
		115778 M9PGE1_DROME (1-423): 5.72e-87: 273: 100.00		M9PGE1_DROME (136-293): 9.56e-16: 80.7: 19.62
+	Dm
		65441 Q4V3F0_DROME (22-333): 1.32e-32: 128: 17.85		A8DZ27_DROME (37-346): 1.92e-63: 207: 32.15
+	Mm
		530211 NCAM1_MOUSE (23-424): 2.14e-59: 211: 11.82		PTK7_MOUSE (55-388): 9.43e-26: 112: 14.50
+	Rn
		530224 NCAM1_RAT (23-424): 5.68e-66: 227: 11.82		Q63237_RAT (175-407): 4.39e-15: 78.6: 9.34
+	Mm
		1149039 CNTN4_MOUSE (16-430): 1.55e-50: 185: 12.70		CNTN4_MOUSE (49-405): 1.7e-22: 102: 9.92
+	Mm
		530206 NCAM1_MOUSE (23-424): 2.14e-59: 211: 11.82		CNTN2_MOUSE (168-397): 3.48e-11: 67.4: 10.26
+	Hs
		1378225 ROBO1_HUMAN (109-428): 2.38e-45: 170: 10.74		ROBO1_HUMAN (164-397): 1.03e-19: 94: 11.30
+	Hs
		1336275 ROBO1_HUMAN (109-428): 2.38e-45: 170: 10.74		ROBO2_HUMAN (200-398): 4.3e-19: 92: 11.77
+	Hs
		1336269 ROBO2_HUMAN (113-428): 2.31e-42: 161: 12.42		ROBO2_HUMAN (200-398): 4.3e-19: 92: 11.77
+	Ce
		103933 SAX3_CAEEL (121-424): 9.6e-39: 151: 14.79		SAX3_CAEEL (202-405): 4.19e-20: 94.7: 13.33
+	Dm
		1097652 LACH_DROME (22-274): 9.72e-37: 139: 19.39		LACH_DROME (57-287): 1.89e-20: 93.8: 19.86
+	Dm
		51388 A8JNC7_DROME (22-346): 3.94e-41: 153: 15.85		A1Z6H9_DROME (25-152): 1.6e-12: 70: 16.15
+	Dm
		1308435 Q9BN17_DROME (2-320): 1.02e-38: 151: 16.57		Q9VAR6_DROME (47-292): 1.74e-10: 64.2: 14.13
+	Dm
		65500 A8JNC7_DROME (22-346): 3.94e-41: 153: 15.85		Q9VFD9_DROME (35-188): 1.36e-09: 61.9: 12.58
+	Hs
		1034838 NTRI_HUMAN (32-313): 7.1e-33: 128: 15.52		LSAMP_HUMAN (60-287): 4.03e-18: 86.8: 20.74
+	Dm
		56434 Q4V3F0_DROME (22-333): 1.32e-32: 128: 17.85		A1ZBY3_DROME (16-158): 2.5e-12: 69.7: 13.70